- the important or essential part; essence; core;
heart: the pith of the matter.
- significant weight; substance; solidity:
an argument with pith.
- spinal cord or bone marrow.
- strength, force, or vigor; mettle: men of pith.
- to remove the pith from (plants).
- to destroy the spinal cord or brain of.
- to slaughter, as cattle, by severing the spinal cord.
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